Abstract: With the wide application of animal models of human diseases, it is inevitable that laboratory animals will be introduced by universities and research institutes. In order to prevent the potential dominance of implicit infection in laboratory animals caused by stress during the introduction process, which can lead to infection with other animals, isolation facilities should be set up to isolate, quarantine, and observe the introduced animals. We have established the isolation system facility by installing isolators in ordinary environments. Through reasonable layout of facility, strengthening disinfection and sterilization, formulation of standard operation procedures, and strict implementation, we can ensure smoother and safer, improve work efficiency, and ensure the quality of animals.

Key words: isolation system facility, isolation system, isolator, biosafety cabinet

摘要： 随着人类疾病动物模型的广泛应用,各高校和研究所不可避免会引入实验动物。 为防止引入过程中因应激 导致的实验动物免疫力下降而可能发生的隐性感染显性化,进而感染其他动物,应设立隔离设施,对引入动物进行 隔离检疫和观察。 我们通过在普通环境中加装隔离器的方式建立了隔离环境设施。 通过对设施的合理布局、加强 消毒灭菌、制定标准操作流程并严格执行,使运行操作更顺畅、安全,提高工作效率,保障动物品质。

关键词: 隔离环境设施, 隔离环境, 隔离器, 生物安全柜